منابع مشابه
Reinvestigation of a selenopeptide with purportedly high glutathione peroxidase activity.
A 15-amino acid long selenopeptide (15SeP) was recently reported to possess nearly the same catalytic activity as glutathione peroxidase (Gpx) for the reduction of hydrogen peroxide by glutathione (Sun, Y., Li, T. Y., Chen, H., Zhang, K., Zheng, K. Y., Mu, Y., Yan, G. L., Li, W., Shen, J. C., and Luo, G. M. (2004) J. Biol. Chem. 279, 37235-37240). Such a finding is startling considering the hig...
متن کاملOn Glutathione : a Reinvestigation. by Frederick Gowland Hopkins. with a Section in the Text by Leslie
In 1927 Hunter and Eagles (1) published an account of investigations which threw doubt upon the constitution of glutathione as apparently established by myself. At the time I was far from sharing these doubts, but I felt after the appearance of Hunter and Eagles’ paper that it was desirable I should reinvestigate the matter, and, if possible, arrive at a method by which the pure thiol compound ...
متن کاملA Reinvestigation of Cross-sections of Cilia
The cilium was one of the first cell organelles to be investigated with the electron microscope (see Manton and Clarke, 1952; Fawcett and Porter, 1954). Since then, this structure has been widely reinvestigated as improved techniques became available both to the electron microscopist and to the biochemist. In the study reported here, improvements in fixation and the use of the "Markham" rotatio...
متن کاملReinvestigation of the roles of the carboxyl groups of glutathione with yeast glyoxalase I. Implications as to the mechanism and coenzymic role of glutathione.
A number of carboxyl-substituted S-blocked glutathiones have been shown to be competitive inhibitors of yeast glyoxalase I at 25 degrees C, pH 6.6. Amidation of the glycyl carboxyl group of S-(p-bromobenzyl)glutathione has no appreciable effect on binding whilst methylation reduces binding by 8.9-fold, indicating a steric constraint and the possible presence of a hydrogen bond in this region of...
متن کاملReinvestigation of the Effect of Iron on Toxin
In diseases such as diphtheria and tetanus, almost all the clinical symptoms terminating in deat.h are due to specific soluble toxins produced in civo (or in vitro) by the diphtheria and t&anus bacilli respectively. Although diphtheria toxin has been isolated as an essentially pure protein which has been reasonably well characterized both chemically and physically (l-3), almost’ nothing is know...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1929
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)77062-2